Search results for "Geriatric population"

showing 5 items of 5 documents

Oxidative stress is related to frailty, not to age or sex, in a geriatric population

2017

Age-associated frailty is a geriatric syndrome. Frail individuals are vulnerable and lack capacity to manage external stressors. Frailty is associated with oxidative stress, but it has not been addressed in a large controlled human cohort. We aimed to ascertain whether indicators of oxidative damage to lipids and proteins are biomarkers of frailty, after adjusting for age, sex, and other possible confounders. We measured lipid and protein oxidation in the Toledo Study for Healthy Aging participants (N=742, aged 65–95), classified as frail, prefrail and nonfrail according to the Fried criteria. We found that age- and sex-adjusted levels of MDA and protein carbonylation in plasma proved to be…

Gerontologybusiness.industryProtein CarbonylationStressorConfoundingContext (language use)Protein oxidationmedicine.disease_causeBiochemistryGeriatric populationPhysiology (medical)CohortmedicinebusinessOxidative stressFree Radical Biology and Medicine
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Malnutrition in elderly: Social and economic determinants

2013

Abstract: Malnutrition occurs frequently in the frailest groups of the population, especially in people who are on a low income and elderly subjects, overall if they are institutionalized. The aim of this study was to assess the prevalence of malnutrition in a sample of elderly people living in different settings and to identify the determinants of malnutrition. Methods: A total of 718 subjects, 472 females (F) and 246 males (M), were recruited from nursing homes or were free living in three different regions in Italy. Nutritional status, depression, social, functional and cognitive status, were evaluated. Results: According to the Mini Nutritional Assessment (MNA), a high prevalence of mal…

Low incomeGerontologyMaleSettore MED/09 - Medicina InternapovertyMalnutrition elderly poverty.PopulationNutritional StatusMedicine (miscellaneous)Guidelines as TopicelderlyGeriatric populationRisk Factorspoverty; elderly; malnutrition80 and overPrevalenceElderly peopleMedicineHumanseducationGeriatric AssessmentDepression (differential diagnoses)AgedAged 80 and overeducation.field_of_studyNutrition and Dieteticsbusiness.industryMalnutritionNutritional statuselderly; Malnutrition; poverty; Aged; Aged 80 and over; Female; Geriatric Assessment; Guidelines as Topic; Humans; Italy; Male; Malnutrition; Nursing Homes; Nutrition Assessment; Nutritional Status; Prevalence; Risk Factors; Socioeconomic Factors; Medicine (miscellaneous); Nutrition and Dietetics; Geriatrics and Gerontologymedicine.diseaseNursing HomesMalnutritionNutrition AssessmentItalySocioeconomic FactorsFemaleGeriatrics and GerontologybusinessNursing homes
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Relationship between childhood physical abuse and clinical severity of treatment-resistant depression in a geriatric population

2021

Introduction We assessed the correlation between childhood maltreatment (CM) and severity of depression in an elderly unipolar Treatment-Resistant Depression (TRD) sample. Methods Patients were enrolled from a longitudinal cohort (FACE-DR) of the French Network of Expert TRD Centres. Results Our sample included 96 patients (33% of the overall cohort) aged 60 years or above, with a mean age of 67.2 (SD = 5.7). The majority of the patients were female (62.5%). The Montgomery and Asberg Depression Rating Scale (MADRS) and Quick Inventory Depression Scale-Self Report (QIDS-SR) mean scores were high, 28.2 (SD = 7.49) [MADRS score range: 0–60; moderate severity≥20, high severity≥35] and 16.5 (SD…

MaleEpidemiologyEmotionsSocial SciencesCriminologyPediatricsSeverity of Illness IndexGeriatric DepressionDepressive Disorder Treatment-Resistant0302 clinical medicineSociologyAdverse Childhood ExperiencesMedicine and Health SciencesPsychologyPublic and Occupational HealthChild AbuseDepression (differential diagnoses)Aged 80 and overeducation.field_of_studySchoolsMultidisciplinaryDepression[SDV.MHEP.GEG]Life Sciences [q-bio]/Human health and pathology/Geriatry and gerontologyTraumatic Injury Risk FactorsQRMiddle AgedPhysical abuseCohortMedicineFemaleCrimeFranceResearch ArticlePersonalitymedicine.medical_specialtyPsychometricsScienceGeriatric PsychiatryPopulationEducation03 medical and health sciencesRating scaleGeriatric populationInternal medicineMental Health and PsychiatrymedicineHumanseducationAgedPersonality TraitsPsychiatric Status Rating ScalesDepressive Disorder MajorMood Disordersbusiness.industryCTQ treeBiology and Life Sciencesmedicine.disease030227 psychiatryHealth CareGeriatricsMedical Risk Factors[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieGeriatric CareSelf ReportbusinessTreatment-resistant depression030217 neurology & neurosurgery
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Frailty Is Associated with Oxidative Stress in Older Patients with Type 2 Diabetes

2021

Aging has increased the prevalence of frailty, and type 2 diabetes (T2D) has also increased in prevalence. Diabetes and oxidative stress (OS) have been shown to be related to frailty. However, the exact mechanism by which it occurs is not fully known. Our aim was to analyze body composition in community-dwelling older diabetic people treated in our center and to evaluate the possible relation between OS, frailty, and body composition. We included 100 adults older than 65 years with T2D. We found that 15% were frail and 57% were prefrail. The patients included in the nonrobust group showed increased levels of OS. Our study shows that the presence of T2D in the geriatric population is associa…

Malemedicine.medical_specialtyPopulationType 2 diabetesfrailtymedicine.disease_causeArticleCohort StudiesProtein CarbonylationOlder patientsGeriatric populationInternal medicineDiabetes mellitusMalondialdehydemedicinePrevalenceHumansoxidative stressTX341-641educationAgededucation.field_of_studybody compositionNutrition and Dieteticsdiabetesbusiness.industryNutrition. Foods and food supplyagingmedicine.diseaseDiabetes Mellitus Type 2Linear ModelsFemalebusinessOxidative stressFood ScienceNutrients
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Potentially inappropriate prescribing in institutionalised older patients in Spain: the STOPP-START criteria compared with the Beers criteria

2011

Objective: The aims of this study were to identify potentially inappropriate prescribing using the Beers and STOPP criteria. The START criteria were applied to detect prescription omission in the geriatric population. We compared the utility of these criteria in institutionalised older people. Methods: Descriptive study reviewing the medication and clinical records of 81 residents (aged 65 years and more) by pharmacists in a nursing home in the Lleida region (Spain). Results: The mean patients´ age was 84 (SD=8) years, with an average of 5 drugs per resident (total prescriptions: 416 medicines). The Beers criteria identified potentially inappropriate medication use in 25% of patients and 48…

Pediatricsmedicine.medical_specialtymesh:Inappropriate Prescribingbusiness.industrySTOPP START CriteriaStopp criteriaBeers CriteriaInappropriate Prescribingmesh:Agedmesh:SpainNursing HomesOlder patientsSpainGeriatric populationIntervention (counseling)Family medicinemesh:Nursing HomesMedicineMedical prescriptionNursing homesbusinessOriginal ResearchAgedPharmacy Practice (Internet)
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